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AI-Based Anomaly Detection for Clinical-Grade Histopathological Diagnostics

Jonas Dippel
Niklas Prenißl
Julius Hense
Philipp Liznerski
Tobias Winterhoff
Simon Schallenberg
Marius Kloft
Oliver Buchstab
David Horst
Maximilian Alber
Lukas Ruff
Klaus-Robert Müller
Frederick Klauschen

October 18, 2024

While previous studies of artificial intelligence (AI) have shown its potential for diagnosing diseases using imaging data, clinical implementation lags behind. AI models require training with large numbers of examples, which are only available for common diseases. In clinical reality, however, the majority of diseases are less frequent, and current AI models overlook or misclassify them. An effective, comprehensive technique is needed for the full spectrum of real-world diagnoses.